Why the study?
Do enalapril and lisinopril alter reflex control of heart rate in normotensive men?
Population
10 normotensive males
Design
Other
Follow-up
7 days
Authors
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ACE inhibitors may impair vagal HR reflexes in normotensives; leaves open contribution to absent reflex tachycardia in hypertension.
Do enalapril and lisinopril alter reflex control of heart rate in normotensive men?
Converting enzyme inhibitors reduce blood pressure without causing reflex tachycardia, likely due to increased parasympathetic activity rather than impaired baroreflexes or sympathetic function.
Ajayi et al. (1985) studied this question.
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