Key result
Real-time 3-dimensional echocardiography was feasible for assessing ventricular volume, mass, and function in 88% of normal fetuses and 43% of fetuses with congenital heart disease.
Why the study?
Is real-time 3-dimensional echocardiography (RT3DE) feasible and reproducible for assessing ventricular volume, mass, and function in human fetuses?
Population
80 pregnant women in the 2nd and 3rd trimesters. Normal group: maternal age 18-42 years, mean gestational…
Design
Cohort, Images were scored and analyzed by two blinded independent observers.
Authors
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Supports RT3DE feasibility for fetal ventricular assessment; leaves open clinical adoption in congenital heart disease pending validation.
Observational (n=80)
Single-blind
No
Is real-time 3-dimensional echocardiography (RT3DE) feasible and reproducible for assessing ventricular volume, mass, and function in human fetuses?
Real-time 3-dimensional echocardiography is a feasible and reproducible modality for assessing fetal ventricular volume, mass, and function, demonstrating exponential gestational growth of these parameters in normal fetuses.
Zheng et al. (2013) conducted an observational in Normal fetuses and fetuses with congenital heart disease (n=80). Real-time 3-dimensional echocardiography (RT3DE) was evaluated on Feasibility of RT3DE data sets for analysis in normal fetuses. Real-time 3-dimensional echocardiography was feasible for assessing ventricular volume, mass, and function in 88% of normal fetuses and 43% of fetuses with congenital heart disease.
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