Key result
Intrauterine growth restriction was associated with a significantly smaller ascending aortic diameter and a higher aortic pressure augmentation index in young adulthood (P < 0.05).
Why the study?
Does intrauterine growth restriction (IUGR) alter cardiac and vascular geometry and function in young adulthood?
Population
37 young adults, including 19 born at term after intrauterine growth restriction and 18 controls, previously…
Comparison
Intrauterine growth restriction with abnormal… vs Controls born at term without IUGR
Design
Cohort
Follow-up
22-25 years
Authors
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May flag elevated long-term CV risk in IUGR survivors; leaves open causal confirmation and screening implications.
Cohort (n=37)
Does intrauterine growth restriction (IUGR) alter cardiac and vascular geometry and function in young adulthood?
p-value: p=<0.05
Intrauterine growth restriction is associated with smaller aortic dimensions and higher systolic blood pressure augmentation in young adulthood, suggesting increased long-term cardiovascular risk.
Bjarnegård et al. (2012) conducted a cohort in Intrauterine growth restriction (n=37). Intrauterine growth restriction vs. Controls (born without intrauterine growth restriction) was evaluated on Ascending aortic diameter and aortic pressure augmentation index (p=<0.05). Intrauterine growth restriction was associated with a significantly smaller ascending aortic diameter and a higher aortic pressure augmentation index in young adulthood (P < 0.05).
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