Key result
Obesity was associated with a significantly higher prevalence of masked hypertension compared with normal weight children (31.6% vs. 5.7%; p=0.0026).
Why the study?
The study was conducted to analyze ambulatory blood pressure data in office normotensive obese children, determine the prevalence and characteristics of masked hypertension, and assess the impact of parental hypertension on ambulatory blood pressure.
Do obesity and parental hypertension increase the prevalence of masked hypertension in office normotensive children?
Cross-Sectional (n=114)
Do obesity and parental hypertension increase the prevalence of masked hypertension in office normotensive children?
Absolute Event Rate: 31.6% vs 5.7%
p-value: p=0.0026
Obese children with normal office blood pressure have a significantly higher prevalence of masked hypertension, which is further exacerbated by parental hypertension.
Obese children with parental hypertension may show higher masked hypertension rates on ABP; cross-sectional data leaves causal and screening implications open.
Objectives The objectives of this study were to analyze ambulatory blood pressure (ABP) data in office normotensive obese children, to determine the prevalence and characteristics of masked hypertension (MH) and to investigate the impact of parental hypertension (PH) on ABP. Methods Seventy-nine obese and 35 normal weight children were enrolled. Each weight group was further divided in accordance with the presence of PH. ABP was recorded in an outpatient setting. Results Obese children had higher systolic ABP (p<0.05) and heart rate (p<0.001) compared with normal weight children. In obese children with PH, only nighttime systolic ABP (p=0.01) was higher compared with obese without PH, whereas normal weight children with PH had higher 24 h and daytime systolic and diastolic BP (all p<0.05) and nighttime DBP (p<0.001) compared with those without PH. PH but not obesity was associated with nondipping phenomenon. Prevalence of MH in the whole group was 23.6% being significantly higher in obese than in nonobese subjects (31.6 vs. 5.7%; p=0.0026) as well as in obese subjects with PH compared with obese subjects without PH (48.7 vs. 15%; χ2=10.37; p=0.001). MH was diagnosed more frequently in obese with high-normal office BP compared with obese with normal office BP, although it did not reach statistical significance (50 vs. 26.2%; χ2=3.631; p=0.056). In the normal weight group, neither PH nor office BP category had an impact on the prevalence of MH. Conclusions Office normotensive obese children had higher ABP values. MH was associated with obesity, PH and high-normal BP.
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Morić et al. (2020) conducted a cross-sectional in Obesity and masked hypertension (n=114). Obesity vs. Normal weight was evaluated on Prevalence of masked hypertension (p=0.0026). Obesity was associated with a significantly higher prevalence of masked hypertension compared with normal weight children (31.6% vs. 5.7%; p=0.0026).
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