Population
Mouse Ltk- cell line stably expressing HK2 (Kv1.5) K+ channel cloned from human ventricle
Comparison
Stable mammalian cell culture expression of HK2… vs Sham transfected cell lines
Design
Preclinical
Authors
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May underlie native delayed rectifier currents in myocytes; leaves open Kv1.5 role in human ventricular repolarization.
The cloned human ventricular HK2 (Kv1.5) channel exhibits properties of a rapidly activating, slowly inactivating delayed rectifier potassium current similar to those found in adult rat atrial and neonatal canine epicardial myocytes.
Snyders et al. (1993) studied this question.
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