Why the study?
Does high-dose aspirin (3.6 grams daily) improve prevention of venous thromboembolic disease compared to low-dose aspirin (1.2 grams daily) in patients over 40 years old undergoing total hip replacement?
Does high-dose aspirin (3.6 grams daily) improve prevention of venous thromboembolic disease compared to low-dose aspirin (1.2 grams daily) in patients over 40 years old undergoing total hip replacement?
High-dose aspirin (3.6 grams daily) is not more effective than low-dose aspirin (1.2 grams daily) for VTE prophylaxis following total hip replacement.
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High-dose aspirin is not superior to low-dose for VTE prophylaxis after hip replacement; confirms dose equivalence and supports low-dose regimens in practice and trials.
Harris et al. (1982) studied this question.
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