Why the study?
Does chronic beta 1-adrenoceptor blocker therapy alter the gene expression of G-protein subunits in human atrium?
Does chronic beta 1-adrenoceptor blocker therapy alter the gene expression of G-protein subunits in human atrium?
Beta 2-adrenoceptor sensitization induced by beta 1-blockade in human atria is unlikely to be mediated by altered gene expression of G-protein subunits.
No takes yet. Share an insight, caveat, or question.
No change in atrial G-protein mRNA with beta1-blockade; leaves open post-transcriptional mechanisms for beta2-sensitization.
Jia et al. (1995) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: