Why the study?
Does chronic beta1-adrenoceptor antagonist treatment alter the gene expression of adenylate cyclase subtypes and beta-adrenoceptor kinase 1 in human atrium?
Does chronic beta1-adrenoceptor antagonist treatment alter the gene expression of adenylate cyclase subtypes and beta-adrenoceptor kinase 1 in human atrium?
Chronic beta1-adrenoceptor blockade does not change the absolute levels of gene expression of adenylate cyclase subtypes in the human atrium.
No takes yet. Share an insight, caveat, or question.
No support for transcriptional adaptation to chronic beta1-blockade in human atrium; leaves open post-transcriptional effects in prospective studies.
Wang et al. (2001) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: