Population
Membranes from human right atria
Design
Preclinical
Authors
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Foundational for atrial adrenergic models; leaves open whether β1-selectivity alters clinical outcomes.
Demonstrates that both β1- and β2-adrenoceptors are functionally coupled to adenylate cyclase in the human right atrium, providing foundational knowledge on cardiac adrenergic signaling.
Brodde et al. (1984) studied this question.
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