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January 1, 1973Acta Physiologica Scandinavica

Circulatory Responses to Stimulation of Medullated and Non‐medullated Afferents in the Cardiac Nerve in the Cat

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Population

Cats (preclinical model)

Comparison

Selective stimulation of medullated and… vs Comparison between medullated and non-medullated…

Design

Preclinical

Authors

BÖBengt ÖBergUniversity of GothenburgPTPeter ThorénCross-Cutting Cardiology

Discussion

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Implication

Animal data delineate opposing reflex arcs from cardiac afferents; leaves open translation to human hemodynamics or disease.

Structured PICO

P
Population
Cats (preclinical model)
I
Intervention
Selective stimulation of medullated and non-medullated afferents in the right main cardiac nerve
C
Comparator
Comparison between medullated and non-medullated fibre stimulation
O
Outcome
Changes in blood pressure, heart rate, and skeletal muscle and renal flow resistancessurrogate

In a feline model, powerful reflex cardiovascular depression is mediated by non-medullated cardiac afferents, whereas medullated afferents exert minor excitatory effects.

Cite This Study

ÖBerg et al. (1973) studied this question.

synapsesocial.com/papers/6a7609d8554f5a6e3e613ac5https://doi.org/10.1111/j.1748-1716.1973.tb05373.x
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Pressor Reflexes Produced by Stimulation of Afferent Fibers in the Cardiac Sympathetic Nerves of the Cat1971 · 109 citations
  2. 2An analysis of the reflex systemic vasodilator response elicited by lung inflation in the dog1968 · 83 citations
  3. 3Circulatory Effects of Interruption and Stimulation of Cardiac Vagal Afferents1970 · 119 citations
  4. 4The effects of distension of the pulmonary vein—atrial junctions upon peripheral vascular resistance1970 · 61 citations
  5. 5Reflex Effects of Left Ventricular Distention1960 · 72 citations