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March 28, 2007Journal of Hypertension

Clustering of metabolic syndrome risk factors and arterial stiffness in young adults: the Northern Ireland Young Hearts Project

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Why the study?

Does the clustering of metabolic syndrome risk factors increase arterial stiffness in young adults?

Population

313 young men and women (mean age 23 years) from the Northern Ireland Young Hearts Project

Comparison

Clustering of metabolic syndrome risk factors vs Subjects without risk factors of the metabolic…

Design

Cross-sectional

Authors

IFIsabel FerreiraHebron UniversityCBColin BorehamUniversity College DublinJTJos W. R. TwiskCardiac Imaging

Discussion

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Implication

MetS associated with greater stiffness in young women; hypothesis-generating for causality, requires prospective confirmation before practice implications.

Structured PICO

Does the clustering of metabolic syndrome risk factors increase arterial stiffness in young adults?

P
Population
313 young men and women (mean age 23 years) from the Northern Ireland Young Hearts Project
I
Intervention
Clustering of metabolic syndrome (MetS) risk factors
C
Comparator
Subjects without risk factors of the metabolic syndrome
O
Outcome
Arterial stiffness assessed by pulse wave velocity (PWV) in three arterial segments (aorto-iliac, aorto-radial, and aorto-dorsalis pedis)surrogate

Metabolic syndrome is associated with increased central and peripheral arterial stiffness in young women, a relationship largely mediated by low-grade inflammation and insulin resistance.

Cite This Study

Ferreira et al. (2007) studied this question.

synapsesocial.com/papers/6a760ca0fa1990f79e613b3bhttps://doi.org/10.1097/hjh.0b013e3280a94e76
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