Why the study?
Does metabolic syndrome and its specific component clusters impact arterial structure and function similarly in men and women?
Population
6,148 subjects, aged 14-102, from a cluster of four towns in Sardinia, Italy.
Comparison
Metabolic syndrome and specific clusters of its… vs Subjects without metabolic syndrome (controls)
Design
Cross-sectional
Authors
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MetS links to greater arterial thickness, stiffness, and diameter dose-dependently and similarly by sex; leaves open whether component-targeted interventions alter vascular outcomes.
Does metabolic syndrome and its specific component clusters impact arterial structure and function similarly in men and women?
Metabolic syndrome accelerates age-associated arterial changes similarly in men and women, with the burden increasing alongside the number of altered components.
Scuteri et al. (2009) studied this question.
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