What question did this study set out to answer?

This study investigates the association between metabolic syndrome and the structural and functional abnormalities of large arteries.

September 1, 2005American Journal of HypertensionOpen Access

Metabolic Syndrome in Relation to Structure and Function of Large Arteries: A Predominant Effect of Blood PressureA Report From the SU.VI.MAX. Vascular Study

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Why the study?

Is metabolic syndrome associated with structural and functional alterations of large arteries in middle-aged adults?

Population

917 middle-aged French men and women participating in the SU.VI.MAX Vascular study

Comparison

Metabolic syndrome defined by the National… vs Subjects without MetS

Design

Cross-sectional

Authors

SCS. CzernichowInserm SBSandrine BertraisInserm JBJacques BlacherPreventive Cardiology

Discussion

Member takes

Implication

MetS warrants closer arterial monitoring in middle-aged adults; confirms BP dominance and extends RCT evidence on vascular changes.

Key Points

This study investigates the association between metabolic syndrome and the structural and functional abnormalities of large arteries.
Included 917 middle-aged French men and women from the SU.VI.MAX Vascular study.
Assessed aortic stiffness using carotid-femoral pulse wave velocity and measured intima-media thickness at common carotid arteries.
Evaluated atherosclerotic plaques in extracranial carotid arteries.
Prevalence of metabolic syndrome was 8.7%; subjects with metabolic syndrome had significantly higher CCA-IMT (P = .02) and pulse wave velocity (P = .0001).
No significant relation between metabolic syndrome and presence of carotid plaques was observed.
Blood pressure was the only component of metabolic syndrome consistently associated with arterial parameters.

Structured PICO

Is metabolic syndrome associated with structural and functional alterations of large arteries in middle-aged adults?

Population

917 middle-aged French men and women participating in the SU.VI.MAX Vascular study

Intervention

Metabolic syndrome (MetS) defined by the National Cholesterol Education Program

Comparator

Subjects without MetS

Outcome

Carotid-femoral pulse wave velocity (aortic stiffness), common carotid artery intima-media thickness (CCA-IMT), and presence of carotid plaquessurrogate

Cite This Study

Czernichow et al. (2005) studied this question.

synapsesocial.com/papers/6a1017675725bbd5cc607d81 https://doi.org/10.1016/j.amjhyper.2005.04.006

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Metabolic Syndrome in Relation to Structure and Function of Large Arteries: A Predominant Effect of Blood PressureA Report From the SU.VI.MAX. Vascular Study

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Metabolic Syndrome in Relation to Structure and Function of Large Arteries: A Predominant Effect of Blood PressureA Report From the SU.VI.MAX. Vascular Study

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Also Consider

Also Consider