August 10, 2006Journal of Applied Physiology

Effects of short-term isocapnic hyperoxia and hypoxia on cardiovascular function

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Why the study?

Do short-term isocapnic hyperoxia and hypoxia alter cardiovascular hemodynamics in healthy men?

Population

8 healthy men

Design

Other

Follow-up

up to 1 hour after restoration of air breathing

Authors

ATA. J. ThomsonUtrecht University GDGordon B. DrummondUK Health Forum WWW. Stephen WaringAstraZeneca (United Kingdom)

Discussion

Member takes

Implication

Alerts to hemodynamic effects of oxygen in normoxic subjects; leaves open translation to patients with cardiovascular disease.

Structured PICO

Do short-term isocapnic hyperoxia and hypoxia alter cardiovascular hemodynamics in healthy men?

Population

8 healthy men

Intervention

1 hour of isocapnic hyperoxia (mean end-tidal O2 79.6 +/- 2.0%) or hypoxia (pulse oximeter oxygen saturation 82.6 +/- 0.3%)

Outcome

Changes in blood pressure (BP), heart rate (HR), cardiac index (CI), systemic vascular resistance index (SVRI) and arterial stiffness (augmentation index, AI)surrogate

Short-term isocapnic hyperoxia and hypoxia cause significant, opposing changes in cardiovascular hemodynamics that are independent of carbon dioxide tension.

Cite This Study

Thomson et al. (2006) studied this question.

synapsesocial.com/papers/6a760e9e1ee3153e8f613a10 https://doi.org/10.1152/japplphysiol.01185.2005

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Ask AI

Bookmark

Effects of short-term isocapnic hyperoxia and hypoxia on cardiovascular function

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Effects of short-term isocapnic hyperoxia and hypoxia on cardiovascular function

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider