Population
Rabbit and frog skeletal muscle homogenates
Design
Preclinical
Authors
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Species differences in skeletal muscle receptor stoichiometry urge caution extrapolating animal data; leaves open precise mechanisms in mammals.
The study demonstrates a significant difference in the stoichiometric ratio of dihydropyridine to ryanodine receptors between rabbit and frog skeletal muscle, informing mechanisms of excitation-contraction coupling.
Anderson et al. (1994) studied this question.
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