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July 1, 1979CirculationOpen Access

Scaling current and energy with body weight: requirements for the transthoracic ventricular defibrillation of calves as they grow from 50 to 150 kg.

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Why the study?

Does scaling defibrillation current to the 2/3 power of body weight and electrode diameter to the 1/3 power maintain consistent defibrillation success as calves grow?

Population

10 calves growing from 50 to 150 kg

Comparison

Transthoracic ventricular defibrillation with… vs Transthoracic ventricular defibrillation with…

Design

Preclinical

Follow-up

Growth from 50 to 150 kg

Authors

JGJ H GoldUniversity of UtahJSJohn C. SchuderUniversity of Missouri Health SystemHSHarry StoeckleUniversity of Missouri Health System

Discussion

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Overview

Supports current scaling for consistent success in calves; extends hypothesis but leaves human translation untested.

Structured PICO

Does scaling defibrillation current to the 2/3 power of body weight and electrode diameter to the 1/3 power maintain consistent defibrillation success as calves grow?

P
Population
10 calves growing from 50 to 150 kg
I
Intervention
Transthoracic ventricular defibrillation with 44-amp, 4-msec rectangular pulses scaled for weight (current proportional to 2/3 power, electrode diameter to 1/3 power)
C
Comparator
Transthoracic ventricular defibrillation with 32-amp, 4-msec rectangular pulses scaled for weight
O
Outcome
First-shock success rate of ventricular defibrillationsurrogate

Scaling defibrillation current to the two-thirds power of body weight maintains consistent defibrillation success across a wide weight range in a calf model when starting with adequate energy.

Cite This Study

Gold et al. (1979) studied this question.

synapsesocial.com/papers/6a7616f3756843cacbb247f6https://doi.org/10.1161/01.cir.60.1.187
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Transthoracic Ventricular Defibrillation in the 100 kg Calf with Symmetrical One-Cycle Bidirectional Rectangular Wave Stimuli1983 · 88 citations
  2. 2Transthoracic ventricular defibrillation in the 100 kg calf with unidirectional rectangular pulses.1977 · 53 citations
  3. 3Electrical Dose for Ventricular Defibrillation of Large and Small Animals Using Precordial Electrodes1974 · 138 citations
  4. 4Transthoracic Ventricular Defibrillation in the 100 kg Calf with Untruncated and Truncated Exponential Stimuli1980 · 70 citations
  5. 5Energy Levels and Patient Weight in Ventricular Defibrillation1979 · 21 citations