Why the study?
Is endothelin involved in the pathogenesis of hypertension?
Population
Hypertensive patients and animals (general discussion)
Design
Review
Authors
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Controversial endothelin data do not alter hypertension care; leaves open whether selective antagonists can clarify its pathogenic role.
Is endothelin involved in the pathogenesis of hypertension?
The role of endothelin in the pathophysiology of hypertension remains unclear and requires further investigation using selective antagonists.
Paul M. Vanhoutte (1993) studied this question.
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