Why the study?
Does endothelin antagonism reduce blood pressure and vascular growth in experimental rat models of hypertension?
Population
Experimental rat models of hypertension
Design
Review
Authors
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Should not change hypertension practice; leaves open human translation of ET antagonism from rat models.
Does endothelin antagonism reduce blood pressure and vascular growth in experimental rat models of hypertension?
Endothelin antagonism shows promise in reducing blood pressure and vascular damage in specific experimental rat models of hypertension, though its role in human hypertension requires further study.
Ernesto L. Schiffrin (2000) studied this question.
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