Preoperative Immunonutrition vs. Standard Dietary Advice in Normo-Nourished Patients Undergoing Fast-Track Laparoscopic Colorectal Surgery
Why the study?
Immunonutrition appears to reduce infective complications and length of stay after major gastrointestinal surgery, but its use in normo-nourished patients remains controversial.
Does preoperative immunonutrition reduce in-hospital length of stay in normo-nourished patients undergoing laparoscopic colorectal surgery?
Population
Normo-nourished patients undergoing ERAS laparoscopic colorectal resection for cancer
Comparison
Preoperative immunonutrition vs standard dietary advice
Design
Comparative observational study
Authors
Discussion
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Member takes
Implication
Preoperative immunonutrition may shorten LOS in ERAS colorectal cancer surgery; leaves open need for RCTs before practice change.
Structured PICO
Does preoperative immunonutrition reduce in-hospital length of stay in normo-nourished patients undergoing laparoscopic colorectal surgery?
P
Population
Normo-nourished patients undergoing laparoscopic colorectal resection for cancer under an enhanced recovery after surgery (ERAS) program between December 2016 and December 2019
I
Intervention
Preoperative immunonutrition (IN)
C
Comparator
Standard dietary advice
O
Outcome
In-hospital length of stay (LOS)
Preoperative immunonutrition associated with an ERAS protocol in normo-nourished patients undergoing laparoscopic colorectal cancer resection significantly reduces in-hospital length of stay.
Cite This Study
Tesauro et al. (2021) studied this question.