June 1, 2002Shock

Increased Hepatosplanchnic Inflammation Precedes the Development of Organ Dysfunction After Elective High-Risk Surgery

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Population

26 high-risk surgical patients undergoing major abdominal surgery in a 24-bed university-affiliated…

Design

Cohort

Follow-up

36 hours postoperatively for measurements, clinical…

Authors

MPMartijn PoezeMaastricht University GRGraham RamsayNational Gallery of Art WBW. A. BuurmanMaastricht University

Discussion

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Implication

May precede postoperative hepatic dysfunction; hypothesis-generating for regional cytokine monitoring in high-risk surgery.

Structured PICO

Population

26 high-risk surgical patients undergoing major abdominal surgery in a 24-bed university-affiliated intensive care unit.

Outcome

Hepatosplanchnic production and uptake of inflammatory mediators (IL-6, IL-8, s-E-selectin, s-ICAM-1, TNF-receptors 55 and 75) and hepatosplanchnic perfusionsurrogate

Increased regional inflammatory response and hepatosplanchnic blood flow with intramucosal acidosis precede the development of postoperative hepatic dysfunction in high-risk surgical patients.

Cite This Study

Poeze et al. (2002) studied this question.

synapsesocial.com/papers/6a761df1b52b7ee7dcfbdd4a https://doi.org/10.1097/00024382-200206000-00002

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Increased Hepatosplanchnic Inflammation Precedes the Development of Organ Dysfunction After Elective High-Risk Surgery

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Increased Hepatosplanchnic Inflammation Precedes the Development of Organ Dysfunction After Elective High-Risk Surgery

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider