Key result
Thiazide therapy reverses hypertension and electrolyte abnormalities long-term in Gordon's syndrome.
Case Report (n=1)
No
Answers are grounded in this paper and cite their sources.
An excellent response to treatment with thiazide diuretic for twelve years is described in a patient with Gordon's Syndrome, the first to be reported from Scotland, and only the second to manifest the full clinical picture of short stature, hypertension, hyperkalaemia and hyperchloraemic acidosis without renal failure. The hypertension and biochemical abnormalities were reversed during therapy. Temporary withdrawal after seven years was followed by the immediate return of all the biochemical abnormalities, but not of the hypertension.
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Gordon et al. (1986) conducted a case report in Gordon's Syndrome (hypertension and hyperkalaemia without renal failure) (n=1). Thiazide diuretic vs. Temporary treatment withdrawal after 7 years was evaluated on Reversal of hypertension and biochemical abnormalities (hyperkalaemia and hyperchloraemic acidosis). Thiazide diuretic therapy for 12 years reversed hypertension and biochemical abnormalities in 1 patient with Gordon's Syndrome, though abnormalities returned upon withdrawal at 7 years.
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