Why the study?
Does low serum ACE activity predict clinical outcomes in patients with community-acquired pneumonia?
Population
265 patients with community-acquired pneumonia, mean age 60±19 years.
Comparison
Low serum ACE activity measured at hospital… vs Normal serum ACE activity (≥20 U/L)
Design
Cohort
Authors
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Low ACE activity may flag bacteremia in CAP without prognostic value; hypothesis-generating and requires prospective validation before clinical use.
Does low serum ACE activity predict clinical outcomes in patients with community-acquired pneumonia?
Low serum ACE activity at hospitalization for community-acquired pneumonia is an independent indicator of bacteremia but does not predict mortality or length of stay.
Meijvis et al. (2011) studied this question.
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