Why the study?
Are low diastolic blood pressure and high pulse pressure associated with greater all-cause mortality in older patients with hypertension?
Population
805 older (≥60 years) subjects with hypertension
Comparison
Ambulatory and office blood pressure monitoring vs Different quartiles of blood pressure and pulse…
Design
Cohort
Follow-up
mean 3.8 years
Authors
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Low ambulatory DBP and high PP were associated with higher mortality in older hypertensives; leaves open whether PP-guided therapy improves outcomes.
Are low diastolic blood pressure and high pulse pressure associated with greater all-cause mortality in older patients with hypertension?
In older hypertensive patients, low diastolic blood pressure and high pulse pressure on ambulatory monitoring are associated with increased mortality, suggesting systolic blood pressure goals should not be achieved at the expense of excessive diastolic blood pressure reduction.
Ungar et al. (2009) studied this question.
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