Why the study?
Do phenothiazine tranquilizing drugs cause sudden unexplained death in psychiatric patients?
Population
Psychiatric patients being treated with phenothiazine tranquilizing drugs, mostly young and in apparent good…
Design
Review
Authors
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May signal sudden death risk with phenothiazines; leaves open causality and mechanisms pending controlled studies.
Do phenothiazine tranquilizing drugs cause sudden unexplained death in psychiatric patients?
Phenothiazine use in psychiatric patients is associated with unpredictable sudden death, possibly mediated by severe cardiac arrhythmias or hypotension.
Jan E. Leestma (1968) studied this question.
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