Key result
Phenothiazines are frequently implicated in the sudden death of psychiatric patients, though this conclusion is often confounded by incomplete death investigations and autopsies.
Why the study?
Do neuroleptics (phenothiazines) cause sudden death in psychiatric patients?
Do neuroleptics (phenothiazines) cause sudden death in psychiatric patients?
Highlights the need for thorough death investigations and autopsies before implicating phenothiazines as the definitive cause of sudden death in psychiatric patients.
A case report illustrates possible pathophysiological mechanisms of sudden death in psychiatric patients. Difficulties with the tendency to implicate phenothiazines as the cause of death are discussed in light of evidence that the death investigation and autopsy are often incomplete. Some suggestions are made to reduce the risk of a fatal outcome following a violent incident.
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Dolan et al. (1995) studied this question. Phenothiazines are frequently implicated in the sudden death of psychiatric patients, though this conclusion is often confounded by incomplete death investigations and autopsies.
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