Why the study?
Does simultaneous invasive pressure monitoring and phase-contrast magnetic resonance flow provide a feasible alternative to the Fick principle for quantifying pulmonary vascular resistance in patients with suspected pulmonary hypertension or congenital heart disease?
Population
n=24 patients with either suspected pulmonary hypertension or congenital heart disease requiring…
Comparison
Pulmonary vascular resistance calculation using… vs PVR calculated by Fick flow
Design
Cross-sectional
Authors
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Discordance between MR and Fick PVR, especially during vasodilator testing, cautions against interchangeability; leaves open prospective outcome validation in pulmonary hypertension.
Does simultaneous invasive pressure monitoring and phase-contrast magnetic resonance flow provide a feasible alternative to the Fick principle for quantifying pulmonary vascular resistance in patients with suspected pulmonary hypertension or congenital heart disease?
Simultaneous invasive pressure measurement and MR flow data is a feasible and safe method to measure PVR in humans, though agreement with the Fick method worsens under vasodilator testing.
Muthurangu et al. (2004) studied this question.
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