October 15, 1996Journal of NeuroscienceOpen Access

Respiratory Neurons Mediating the Breuer–Hering Reflex Prolongation of Expiration in Rat

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Population

Rat model (ventrolateral medulla respiratory neurons)

Design

Preclinical

Authors

FHFumiaki HayashiRIKEN Center for Biosystems Dynamics Research SCSharon K. ColesUniversity of South Dakota DMDonald R. McCrimmonNorthwestern University

Discussion

Member takes

Implication

Clarifies E-Dec neuron responses in the Breuer-Hering reflex; leaves open translation to human respiratory control or therapies.

Structured PICO

Population

Rat model (ventrolateral medulla respiratory neurons)

Intervention

Lung inflation (7.5 cm H2O) or vagus nerve stimulation (50 Hz)

Outcome

Neuronal response (depolarization/hyperpolarization) during Breuer-Hering reflex activationsurrogate

E-Dec neurons in the ventrolateral medulla likely receive paucisynaptic input from pulmonary afferents to inhibit inspiratory neurons and prolong expiration during the Breuer-Hering reflex.

Cite This Study

Hayashi et al. (1996) studied this question.

synapsesocial.com/papers/6a7645a33025cdd732bcb8ce https://doi.org/10.1523/jneurosci.16-20-06526.1996

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Respiratory Neurons Mediating the Breuer–Hering Reflex Prolongation of Expiration in Rat

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Respiratory Neurons Mediating the Breuer–Hering Reflex Prolongation of Expiration in Rat

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider