Key Points
- To examine predictors of intentional and unintentional nonadherence to antihypertensive medication regimens and evaluate their relationship to blood pressure outcomes in Korean Americans.
- Analyzed cross-sectional baseline data from an ongoing high blood pressure intervention trial involving middle-aged (40–64 years) Korean Americans.
- Included 208 participants on antihypertensive medication out of 445 enrolled at baseline.
- Used multivariate logistic regression models adjusting for demographic covariates to evaluate predictors of intentional and unintentional nonadherence.
- Approximately 53.8% of participants reported engaging in one or more types of medication nonadherent behaviors.
- Intentional nonadherence was significantly associated with a greater number of medication side effects (adjusted OR, 1.19; 95% CI, 1.07 to 1.33) and lower high blood pressure knowledge (adjusted OR, 0.89; 95% CI, 0.79 to 0.99).
- Unintentional nonadherence demonstrated weaker associations with the evaluated knowledge and side-effect variables.
Structured PICO
PPopulation208 middle-aged (40-64 years) Korean Americans with high blood pressure who were on antihypertensive medication
OOutcomeIntentional and unintentional nonadherence to antihypertensive medication regimenspatient reported
Intentional nonadherence to antihypertensive medication is prevalent among middle-aged Korean Americans and is significantly associated with medication side effects and lower hypertension knowledge.