Why the study?
Does endurance exercise attenuate ultrastructural changes in diabetic cardiomyopathy in a rat model?
Population
Seven-week-old rats with streptozotocin-induced diabetes
Comparison
Endurance exercise vs Sedentary diabetic rats and sedentary…
Design
Preclinical
Follow-up
9 weeks
Authors
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May inform human trials on exercise for diabetic cardiomyopathy; leaves open clinical translation from rat models.
Does endurance exercise attenuate ultrastructural changes in diabetic cardiomyopathy in a rat model?
Endurance exercise partially restores specific ultrastructural characteristics of diabetic cardiomyopathy, particularly in mitochondria and extracellular matrix proteins, in a rat model.
Searls et al. (2004) studied this question.
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