Why the study?
Does exercise training prevent the development of cardiac autonomic dysfunction in a rat model of type 1 diabetes mellitus?
Population
Wistar rats, including a model of type 1 diabetes mellitus induced by a single intraperitoneal injection of…
Comparison
8 weeks of exercise training on a treadmill. vs Sedentary control and sedentary diabetic rats.
Design
Preclinical, Randomly assigned to four groups
Follow-up
8 weeks
Authors
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Exercise may benefit autonomic function in diabetic rat models; hypothesis-generating for human cardiac autonomic neuropathy prevention.
Does exercise training prevent the development of cardiac autonomic dysfunction in a rat model of type 1 diabetes mellitus?
Early initiation of systemic exercise training prevents the development of cardiac autonomic neuropathy in a rat model of type 1 diabetes by favorably changing the sympathovagal balance.
Nakos et al. (2018) studied this question.
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