Why the study?
Does exercise training improve hemodynamic and autonomic dysfunction in streptozotocin-diabetic rats?
Population
Male Wistar rats (N = 18) with streptozotocin-induced diabetes (50 mg/kg, iv), weight 222 +/- 5 g
Comparison
Exercise training for 10 weeks on a treadmill vs Sedentary diabetic rats and non-diabetic controls
Design
Preclinical
Follow-up
10 weeks
Authors
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Supports exercise benefits in experimental diabetes; hypothesis-generating and should not change clinical practice.
Does exercise training improve hemodynamic and autonomic dysfunction in streptozotocin-diabetic rats?
Exercise training attenuates hypotension and bradycardia and improves myocardial function in a rat model of diabetes.
Angelis et al. (2000) studied this question.
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