Why the study?
Aldosterone can be affected by factors such as age and its effect on left ventricular function remains controversial, prompting investigation into its relationship with left ventricular geometry and function in young adults with never-treated hypertension.
In young adults with never-treated hypertension, higher serum aldosterone levels correlate with adverse changes in left ventricular geometry and subclinical functional impairment, suggesting a pro-hypertrophic and fibrotic effect beyond blood pressure.
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Aldosterone may link to early LV remodeling in young untreated HT; hypothesis-generating, prospective trials needed before practice change.
Park et al. (2019) studied this question.
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