Key result
Plasma aldosterone levels were associated with left ventricular hypertrophy (found in 21% of patients) but had no independent relationship with left ventricular diastolic properties.
Why the study?
Are plasma aldosterone levels independently associated with left ventricular diastolic function in treatment-naïve patients with hypertension?
Observational (n=215)
Are plasma aldosterone levels independently associated with left ventricular diastolic function in treatment-naïve patients with hypertension?
In treatment-naïve hypertensive patients, plasma aldosterone levels are associated with left ventricular hypertrophy but do not have an independent relationship with left ventricular diastolic properties.
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Aldosterone linked to hypertrophy but not diastolic function in untreated hypertension; hypothesis-generating, needs longitudinal studies before implications.
Catena et al. (2015) conducted an observational in Primary hypertension (n=215). Plasma aldosterone levels vs. Normotensive controls was evaluated on Left ventricular diastolic function. Plasma aldosterone levels were associated with left ventricular hypertrophy (found in 21% of patients) but had no independent relationship with left ventricular diastolic properties.
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