Why the study?
Does plasma ANF correlate with left ventricular diastolic function in hypertensive patients without left ventricular hypertrophy?
Population
42 subjects total: 23 untreated hypertensive patients without left ventricular hypertrophy and 19…
Design
Cross-sectional
Authors
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May signal early diastolic impairment in hypertension without LVH; hypothesis-generating and requires prospective validation before clinical consideration.
Does plasma ANF correlate with left ventricular diastolic function in hypertensive patients without left ventricular hypertrophy?
High plasma ANF levels correlate with impaired left ventricular diastolic function in hypertensive patients before the development of left ventricular hypertrophy, likely reflecting increased atrial stretch.
Dessı̀-Fulgheri et al. (1992) studied this question.
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