Key Points
- To evaluate clinical outcomes, symptom relief, and adverse prognostic factors in patients undergoing coronary artery bypass surgery.
- Reviewed outcomes of 1,276 patients undergoing coronary artery bypass between October 1969 and March 1972.
- Analyzed 1,105 patients receiving bypass alone (with or without endarterectomy) alongside cohorts undergoing concomitant valve replacement or aneurysm repair.
- Adverse risk factors for surgical outcome included concomitant endarterectomy, female sex, advanced age, left ventricular failure or dysfunction, and myocardial infarction within one month (especially within one week) prior to surgery.
- Functional class III and IV angina was significantly decreased or totally relieved in a high percentage of patients.
- Improvements in patient selection and surgical risk reduced the early operative mortality rate to 3.7%.
Structured PICO
PPopulation1,276 patients undergoing coronary artery bypass at the Texas Heart Institute between October 1969 and March 1972, including 1,105 who underwent bypass surgery alone.
IInterventionCoronary artery bypass surgery
OOutcomeEarly mortality and relief of functional class III and IV anginahard clinical
Coronary artery bypass surgery provides significant relief of severe angina with an early mortality risk of 3.7%, though risk is increased by factors like recent MI, female sex, and LV dysfunction.