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May 23, 2005Archives of Internal Medicine

Prevalence and Impact of Metabolic Syndrome on Hospital Outcomes in Acute Myocardial Infarction

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Why the study?

Does the presence of metabolic syndrome increase the risk of in-hospital death and severe heart failure in patients with acute myocardial infarction?

Population

633 unselected, consecutive patients hospitalized with acute myocardial infarction (AMI)

Comparison

Presence of metabolic syndrome vs Absence of metabolic syndrome

Design

Cohort

Follow-up

in-hospital

Authors

MZMarianne ZellerPreventive Cardiology

Discussion

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Implication

Metabolic syndrome may predict severe HF after AMI; hypothesis-generating for hyperglycemia interventions, pending prospective trials.

Structured PICO

Does the presence of metabolic syndrome increase the risk of in-hospital death and severe heart failure in patients with acute myocardial infarction?

P
Population
633 unselected, consecutive patients hospitalized with acute myocardial infarction (AMI)
I
Intervention
Presence of metabolic syndrome (defined by NCEP ATP III criteria)
C
Comparator
Absence of metabolic syndrome
O
Outcome
In-hospital death and incidence of severe heart failure (Killip class >II)hard clinical

Metabolic syndrome, driven primarily by hyperglycemia, is highly prevalent in AMI patients and strongly predicts the development of severe in-hospital heart failure.

Cite This Study

Marianne Zeller (2005) studied this question.

synapsesocial.com/papers/6a7661f798f24dbf64bd2927https://doi.org/10.1001/archinte.165.10.1192
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1In-Hospital Prognosis of Ppatients With Fasting Hyperglycemia After First Myocardial Infarction1991 · 107 citations
  2. 2Myocardial infarction redefined—a consensus document of The Joint European Society of Cardiology/American College of Cardiology committee for the redefinition of myocardial infarction2000 · 4,856 citations
  3. 3Myocardial infarction redefined—A consensus document of The Joint European Society of Cardiology/American College of Cardiology Committee for the Redefinition of Myocardial Infarction2000 · 2,284 citations
  4. 4Role of Insulin Resistance in Human Disease1988 · 12,163 citations
  5. 5Risk Variable Clustering in the Insulin Resistance Syndrome: The Framingham Offspring Study1997 · 511 citations