Why the study?
How do changes in blood volume (expansion and hemorrhage) affect systemic arterial input impedance in anesthetized dogs?
Population
12 anesthetized dogs
Comparison
Volume expansion with dextran 70 and hemorrhage vs Control conditions
Design
Preclinical
Authors
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Volume shifts alter aortic impedance in dogs; leaves open translation to human hemodynamics or volume management.
How do changes in blood volume (expansion and hemorrhage) affect systemic arterial input impedance in anesthetized dogs?
Changes in blood volume significantly alter the characteristic impedance of the proximal aorta, likely driven by changes in aortic smooth muscle activity.
Dujardin et al. (1980) studied this question.
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