Detergent effects, rather than disruption of protein-protein contacts, primarily drive the kinetic differences between solubilized and membrane-bound sarcoplasmic reticulum Ca-ATPase.
No takes yet. Share an insight, caveat, or question.
Caution advised interpreting solubilized Ca-ATPase kinetics; leaves open single-peptide modulation in native cardiac membranes.
Vilsen et al. (1987) studied this question.
Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context: