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November 1, 2004International Journal of Oncology

Abnormal expression of cell cycle regulators in FUS-CHOP carrying liposarcomas

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Authors

AOAnita OlofssonUniversity of Gothenburg HWHelena WillénUppsala University MGMelker GöranssonAstraZeneca (Netherlands)

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Implication

Animal models link FUS-CHOP to MLS-like tumors; leaves open human therapeutic targeting.

Key Points

Key points are not available for this paper at this time.

Cite This Study

Olofsson et al. (2004) studied this question.

synapsesocial.com/papers/6a768d45137c7dcc81bd4170 https://doi.org/10.3892/ijo.25.5.1349

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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Expression of the FUS-CHOP Fusion Protein in Primary Mesenchymal Progenitor Cells Gives Rise to a Model of Myxoid Liposarcoma2006 · 161 citations
2Genomic PCR detects tumor cells in peripheral blood from patients with myxoid liposarcoma1996 · 29 citations
3Additional evidence of a variant translocation t(12;22) withEWS/CHOP fusion in myxoid liposarcoma: clinicopathological features1997 · 113 citations
4Rearrangement of the transcription factor gene <i>CHOP</i> in myxoid liposarcomas with t(12;16)(q13;p11)1992 · 299 citations
5Abstract 6836: Single-cell RNA sequencing of FUS::DDIT3 myxoid/round cell liposarcoma delineates mechanisms of oncogenic progression and immune escape2024