Key result
Myxoid/round cell liposarcoma with a t(12;22) translocation and EWS/CHOP fusion showed no identifiable clinical or pathological differences compared to cases with the usual t(12;16) translocation.
Population
4 cases of myxoid/round cell liposarcoma with t EWS/CHOP fusion
Design
Case_series
Authors
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No management change indicated by translocation variant; larger series needed to confirm equivalence.
Case Report (n=4)
The variant t(12;22) EWS/CHOP fusion in myxoid liposarcoma does not appear to result in different clinicopathological features compared to the classic t(12;16) translocation.
Cin et al. (1997) conducted a case report in Myxoid/round cell liposarcoma (n=4). t(12;22) translocation with EWS/CHOP fusion vs. t(12;16) translocation was evaluated on Clinicopathological differences. Myxoid/round cell liposarcoma with a t(12;22) translocation and EWS/CHOP fusion showed no identifiable clinical or pathological differences compared to cases with the usual t(12;16) translocation.
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