Why the study?
Does local overexpression of thrombomodulin via an adenoviral construct prevent arterial thrombosis in a rabbit stasis/injury model?
Does local overexpression of thrombomodulin via an adenoviral construct prevent arterial thrombosis in a rabbit stasis/injury model?
Local overexpression of thrombomodulin via an adenoviral construct effectively prevents arterial thrombosis and reduces local inflammation in a rabbit model.
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Does not support clinical use of adenoviral thrombomodulin delivery; extends preclinical evidence for local gene therapy in arterial thrombosis models.
Waugh et al. (1999) studied this question.
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