Why the study?
Studies comparing the impact of TAVR versus SAVR by annular size were limited.
Does transcatheter aortic valve replacement lead to similar outcomes compared to surgical aortic valve replacement in low-risk patients with severe aortic stenosis irrespective of annular size?
Does transcatheter aortic valve replacement lead to similar outcomes compared to surgical aortic valve replacement in low-risk patients with severe aortic stenosis irrespective of annular size?
TAVR provides similar 5-year clinical and health status outcomes compared to SAVR in low-risk patients with severe aortic stenosis, regardless of aortic annulus size.
Similar 5-year TAVR and SAVR outcomes across annular sizes support valve choice in low-risk AS; extends PARTNER 3 without size interaction.
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Madhavan et al. (2026) studied this question.
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