In patients with angiographically proven CAD, GGT levels are positively associated with triglycerides and VLDL cholesterol, suggesting a link with traditional cardiovascular risk factors.
May support GGT for CAD risk stratification in north Indians; leaves open incremental value beyond traditional factors.
Gamma glutamyl transferase (GGT) is emerging as a promising marker for assessing cardiovascular risk. GGT predicts cardiovascular mortality in the population and is positively associated with traditional risk factors for coronary artery disease (CAD). This study was undertaken on 200 north Indian CAD patients diagnosed with coronary angiography to study relation of GGT with risk factors for CAD and severity of CAD. GGT values ranged from 5 to 69U/L and were divided in 4 quartiles. GGT was positively associated with triglyceride (p=0.008) and VLDL cholesterol (p=0.002) in our subjects. Also an increase in total cholesterol from GGT quartile I to quartile IV (p=0.28) was noted.
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Bharani et al. (2017) studied this question.
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