Why the study?
Gamma-glutamyltransferase is a recognized cardiovascular risk factor and its big GGT fraction is found in vulnerable plaques, but its relationship with CT findings and long-term outcomes in the general population remained to be explored.
Is big gamma-glutamyltransferase (b-GGT) associated with epicardial fat volume and cardiovascular outcomes in the general population?
Is big gamma-glutamyltransferase (b-GGT) associated with epicardial fat volume and cardiovascular outcomes in the general population?
Big GGT is associated with epicardial fat volume and cardiovascular outcomes, but does not appear more predictive than the commonly available total GGT assay.
b-GGT links to CT plaque burden and events in asymptomatic adults; leaves open incremental prognostic value over standard risk factors.
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Aimo et al. (2021) studied this question.
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