Why the study?
Early diagnosis of chronic overstress among athletes remains challenging, prompting an animal model study to examine autoimmune response dynamics to varied physical activity as an indicator of cardiac morphofunctional state.
Cardiospecific autoantibodies show dynamic changes during adaptation to physical activity in a rat model, highlighting their potential utility as biomarkers for the functional state of the heart muscle.
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May flag cardiac overstress via autoantibodies in animal models; leaves open human diagnostic utility pending clinical trials.
Belyaev et al. (2022) studied this question.
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