Why the study?
Increasing chronic physical overstrain among athletes highlighted the need for early diagnosis of cardiovascular pathology to prevent its progression.
In a rat model of chronic physical overstrain, autoantibodies to cardiomyocyte proteins increased before functional or morphological cardiac changes, suggesting their potential utility for early diagnosis.
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May warrant autoantibody monitoring for early detection in athletes; hypothesis-generating in rats and leaves human translation open.
Levochkina et al. (2022) studied this question.
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