Why the study?
Does high versus low sodium intake affect blood pressure differently based on demographic factors and hypertensive type in individuals with essential hypertension?
Population
274 individuals with essential hypertension
Comparison
High sodium intake (200 mEq) vs Low sodium intake (10 mEq)
Design
Cohort
Authors
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Salt sensitivity varies by gender and hypertension type; hypothesis-generating and should not yet guide personalized sodium restriction.
Does high versus low sodium intake affect blood pressure differently based on demographic factors and hypertensive type in individuals with essential hypertension?
Blood pressure sensitivity to salt intake varies significantly by gender and hypertension type, reducing its usefulness as a simple intermediate phenotype.
Hurwitz et al. (2003) studied this question.
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