Why the study?
Does experimental subarachnoid hemorrhage cause cardiac arrhythmias in dogs through direct autonomic discharges or circulating catecholamines?
Population
Dogs (experimental subarachnoid hemorrhage model)
Comparison
Experimental subarachnoid hemorrhage produced by… vs Intact animals vs. animals with sections of both…
Design
Preclinical
Authors
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May implicate dual neural and humoral pathways in experimental SAH arrhythmias; leaves open human translation and targeted interventions.
Does experimental subarachnoid hemorrhage cause cardiac arrhythmias in dogs through direct autonomic discharges or circulating catecholamines?
Arrhythmias following subarachnoid hemorrhage can be produced by either direct autonomic discharges to the heart or by increased circulating and tissue catecholamines.
Estanol et al. (1977) studied this question.
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