Why the study?
Does a formula calculating the 'Index of Anticoagulation' provide accurate interpretation of prothrombin time results compared to observed values across hospital centers?
Population
132 hospital centres participating in a reference thromboplastin scheme
Comparison
Formula for the interpretation of prothrombin… vs Actual observed values
Design
Cross-sectional
Authors
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Calculated anticoagulation indices differ markedly from observed values; challenges formula utility and leaves standardization approaches open.
Does a formula calculating the 'Index of Anticoagulation' provide accurate interpretation of prothrombin time results compared to observed values across hospital centers?
The use of a formula to calculate the 'Index of Anticoagulation' is not practically useful for standardizing prothrombin time results across different hospitals.
Poller et al. (1969) studied this question.
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