Prevalence, Burden and Echocardiographic Features of Moderate to Severe Tricuspid Regurgitation: Insights from a Tertiary Referral Center
Why the study?
Although systematically underestimated in the past, the importance of tricuspid regurgitation is being progressively recognized, prompting an evaluation of the clinical significance of severe tricuspid regurgitation.
Does severe tricuspid regurgitation increase the risk of cardiovascular mortality and adverse events in patients undergoing echocardiography?
Population
6309 consecutive patients undergoing echocardiography at a single center in Milan, Italy
Comparison
Severe TR vs moderate TR or other TR severities
Design
Single-center retrospective cohort study
Authors
Discussion
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Member takes
Implication
Severe TR was associated with higher cardiovascular mortality; leaves open whether intervention improves outcomes.
Structured PICO
Does severe tricuspid regurgitation increase the risk of cardiovascular mortality and adverse events in patients undergoing echocardiography?
P
Population
6309 consecutive patients undergoing echocardiography between October 2014 and September 2015 in a single center in Milan, Italy.
O
Outcome
Cardiovascular mortality, major adverse cardiac and cerebrovascular events (MACCE) and net adverse clinical events (NACE)composite
Severe tricuspid regurgitation is present in 4.3% of patients undergoing echocardiography at a tertiary center and is associated with significant mid-term morbidity and mortality.
Cite This Study
Montalto et al. (2019) studied this question.